RiteMED Irbesartan Adverse Reactions

The most frequently reported adverse effects with irbesartan in patients with hypertension include diarrhea, dyspepsia/heartburn and fatigue. In patients receiving irbesartan for diabetic nephropathy, the most common adverse effects reported include hyperkalemia, dizziness, orthostatic dizziness, and orthostatic hypotension.
Blood and lymphatic system disorders: Neutropenia, thrombocytopenia.
Immune system disorders: Hypersensitivity reactions such as rash, urticaria, angioedema (involving swelling of the face, lips, pharynx, and/or tongue).
Nervous system disorders: Headache, vertigo.
Ear and labyrinth disorders: Tinnitus.
Cardiac disorders: Tachycardia.
Vascular disorders: Edema.
Respiratory, thoracic and mediastinal disorders: Cough.
Gastrointestinal disorders: Dysgeusia, gastrointestinal disturbances, nausea, vomiting.
Hepatobiliary disorders: Abnormal liver function, hepatitis, jaundice.
Skin and subcutaneous tissue disorders: Leukocytoclastic vasculitis, pruritus.
Musculoskeletal and connective tissue disorders: Arthralgia, back pain, muscle cramps, musculoskeletal pain, myalgia (in some cases associated with increased plasma creatine kinase level), rhabdomyolysis (rare).
Renal and urinary disorders: Impaired renal function including cases of renal failure.
Reproductive system and breast disorders: Sexual dysfunction.
General disorders and administration site conditions: Asthenia, chest pain.
Investigations: Decrease in hemoglobin; increase in liver function tests, BUN, serum creatinine, plasma creatine kinase.